A largely-static site serves 6,000 rps — but almost all of it is images, CSS, and JS being served straight from the origin fleet, which has been scaled up to cope in a single AZ.
Targets: p99 ≤ 150 ms, 99.9% availability, standard durability, under $700/mo.
Put a CloudFront CDN in front to serve static assets from the edge — that offloads most of the traffic, so the origin can be much smaller across two AZs. Add a cache and make the database Multi-AZ with backups.