A worldwide audience needs p99 ≤ 85 ms at 8,000 rps. No matter how you tune a single region, distant users pay the round-trip tax — you simply can't hit 85 ms globally from one place.
Targets: p99 ≤ 85 ms, 99.95% availability, critical durability, under $2,000/mo.
Serve users close to home: a CDN for edge caching plus an active-active multi-region deployment to cut round-trip latency, backed by a right-sized autoscaling tier, a cache, and a Multi-AZ database. Multi-region doubles the compute/database bill, so keep every tier lean.